Aplastic Anemia Secondary to Thymectomy in a Patient With Myasthenia Gravis.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 32135152.
- Also identified by DOI 10.1016/j.athoracsur.2020.01.044.
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Abstract
It is a well-described phenomenon in the literature that a thymoma can lead to aplastic anemia, and that a thymectomy can be curative for to aplastic anemia. However, the opposite is extremely rare. We present an unusual case of a 60-year-old woman with myasthenia gravis, who was diagnosed with an incidental thymoma found on computerized tomography. Resection of the thymoma treated her myasthenia gravis but led to an aplastic anemia resistant to granulocyte colony-stimulating factor, cyclosporin, and horse antithymocyte globulin treatment. The patient received an allogenic stem cell transplant but unfortunately passed away because of complications.
Medical subject headings
- Anemia, Aplastic
- Myasthenia Gravis
- Thymectomy
- Thymoma
- Thymus Neoplasms