"Liquid Gold" - The unTAPped Potential of Cerebrospinal Fluid Analysis?

Glitza Oliva, Isabella C; Tawbi, Hussein A · Clin Cancer Res · 2020

editorial · Level V

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Abstract

Obtaining blood and cerebrospinal fluid is generally less invasive than standard tumor biopsy, and are increasingly used to develop surrogate biomarkers. Leptomeningeal disease, a devastating complication of cancer, represents a unique opportunity for using liquid biopsies for diagnosis, treatment, and to elucidate underlying mechanisms of resistance to therapy.<i>See related article by Smalley et al., p. 2163</i>.

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