Reserving the Right to Change the Intestinal Stem Cell Model.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 32142658.
- Also identified by DOI 10.1016/j.stem.2020.02.003 and PMC identifier 7617120.
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Abstract
The existence of "active" and "reserve" stem cell populations in the intestinal epithelium has been debated since 1977. Now in Cell Stem Cell, Murata et al. (2020) show that all intestinal regeneration arises from daughter cell dedifferentiation, marking the coming-of-age of the regenerative stem cell plasticity model.
Medical subject headings
- Cell Dedifferentiation
- Intestines