Cangrelor and Heparin for Pulmonary Thromboendarterectomy in Heparin-Induced Thrombocytopenia.

Ta, Jackie; Mishra, Suraj; Vaidya, Anjali; Forfia, Paul R; Toyoda, Yoshiya; Auger, William R; Salamanca-Padilla, Y Yuliana; Morewood, Gordon H · Ann Thorac Surg · 2020

case_report · Level V

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Abstract

Perioperative anticoagulation management for patients with heparin-induced thrombocytopenia requiring cardiopulmonary bypass and deep hypothermic circulatory arrest presents a clinical challenge. Alternative anticoagulants have been used but can cause significant postoperative bleeding. We report the successful use of cangrelor and heparin in a 30-year-old patient with severe heparin-induced thrombocytopenia undergoing urgent pulmonary thromboendarterectomy.

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