Genetic Determinants of Pheochromocytoma and Paraganglioma Imaging Phenotypes.
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- Record sourced from PubMed, PMID 32198315.
- Also identified by DOI 10.2967/jnumed.120.245613 and PMC identifier 7198379.
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Abstract
Parallel to the application of new PET radiopharmaceuticals for pheochromocytoma and paraganglioma (collectively named PPGLs) imaging, several studies have increased our understanding on their biology, genetics, metabolomics, and embryologic origin. In this review, we highlight the current relationship between genotypes and molecular imaging phenotypes. Additionally, we summarize the referral guidelines for imaging of PPGL patients with or without knowledge of their genetic background.
Medical subject headings
- Adrenal Gland Neoplasms
- Molecular Imaging
- Phenotype
- Pheochromocytoma