SnapShot: Natural Killer Cells.

Crinier, Adeline; Narni-Mancinelli, Emilie; Ugolini, Sophie; Vivier, Eric · Cell · 2020

review · Level V

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Abstract

NK cells are broadly distributed innate lymphoid cells (ILCs) encompassing distinct populations based on CD11b and CD27 expression in mice or CD56 intensity in humans. Involved in anti-viral and anti-tumor immunity thanks to their cytokines and chemokines secretion as well as their cytotoxic capabilities, NK cells have emerged as a promising therapeutic target in several solid tumors and hematological malignancies. To view this Snapshot, open or download the PDF.

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