An implantable multifunctional neural microprobe for simultaneous multi-analyte sensing and chemical delivery.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 32211718.
- Also identified by DOI 10.1039/d0lc00021c and PMC identifier 7192313.
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Abstract
A multifunctional chemical neural probe fabrication process exploiting PDMS thin-film transfer to incorporate a microfluidic channel onto a silicon-based microelectrode array (MEA) platform, and enzyme microstamping to provide multi-analyte detection is described. The Si/PDMS hybrid chemtrode, modified with a nano-based on-probe IrOx reference electrode, was validated in brain phantoms and in rat brain.
Medical subject headings
- Microfluidics
- Prostheses and Implants