Gastruloids Gain Muscle: Somite Formation in Embryo-Like Structures.

Rosado-Olivieri, Edwin A; Brivanlou, Ali H · Cell Stem Cell · 2020

editorial · Level V

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Abstract

Gastruloids are embryo-like structures that display key features of post-implantation embryonic development, yet whether they fully recapitulate in vivo embryogenesis remains unsolved. Recently in Nature, van den Brink et al. (2020) performed high-resolution gene expression analysis to identify significant similarities between mouse gastruloids and embryos in positional lineage segregation and somite formation.

Medical subject headings