Functional brain network reconfiguration during learning in a dynamic environment.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 32245973.
- Also identified by DOI 10.1038/s41467-020-15442-2 and PMC identifier 7125157.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
When learning about dynamic and uncertain environments, people should update their beliefs most strongly when new evidence is most informative, such as when the environment undergoes a surprising change or existing beliefs are highly uncertain. Here we show that modulations of surprise and uncertainty are encoded in a particular, temporally dynamic pattern of whole-brain functional connectivity, and this encoding is enhanced in individuals that adapt their learning dynamics more appropriately in response to these factors. The key feature of this whole-brain pattern of functional connectivity is stronger connectivity, or functional integration, between the fronto-parietal and other functional systems. Our results provide new insights regarding the association between dynamic adjustments in learning and dynamic, large-scale changes in functional connectivity across the brain.
Medical subject headings
- Frontal Lobe
- Learning
- Models, Neurological
- Nerve Net
- Parietal Lobe