Human airway epithelial cells express a functional IL-5 receptor.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 32246831.
- Also identified by DOI 10.1111/all.14297 and PMC identifier 7387204.
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Abstract
We found that HBEC expressed the IL-5 receptor, which triggered intracellular signaling and changed gene expression. This data indicate that in addition to targeting eosinophils, IL-5 and anti-IL-5 biologics may have a direct role on AEC.
Medical subject headings
- Epithelial Cells
- Interleukin-13