Engineered reproductive tissues.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 32251392.
- Also identified by DOI 10.1038/s41551-020-0525-x and PMC identifier 7416444.
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Abstract
Engineered male and female biomimetic reproductive tissues are being developed as autonomous in vitro units or as integrated multi-organ in vitro systems to support germ cell and embryo function, and to display characteristic endocrine phenotypic patterns, such as the 28-day human ovulatory cycle. In this Review, we summarize how engineered reproductive tissues facilitate research in reproductive biology, and overview strategies for making engineered reproductive tissues that might eventually allow the restoration of reproductive capacity in patients.
Medical subject headings
- Genitalia, Female
- Genitalia, Male
- Reproduction
- Tissue Engineering