Hypovitaminosis D in lower extremity Joint Arthroplasty: A systematic review and meta-analysis.
systematic_review · Level I
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- Record sourced from PubMed, PMID 32255990.
- Also identified by DOI 10.1016/j.jor.2020.03.010 and PMC identifier 7114851.
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Abstract
The purpose of the current systematic review was to identify the prevalence of hypovitaminosis-D in LE-TJA patients; and outline the association between pre-operative hypovitaminosis and post-operative outcomes. A search of PubMed-Medline and the Cochrane-Library databases was performed for literature published before November 27th, 2019<b>.</b> The eighteen studies analyzed had a pooled prevalence for vitamin D insufficiency (20 - <30 ng/mL) and deficiency (<20 ng/mL) of 53.4% and 39.4%, respectively. Hypovitaminosis-D was associated with higher complication rates (<i>p</i> = 0.043), and a greater prevalence among septic versus aseptic revisions (<i>p</i> = 0.016). Therefore, pre-operative screening for hypovitaminosis-D can be beneficial in patients undergoing LE-TJA. Systematic Review (Level III).