Biocompatibility of biphasic α,β-tricalcium phosphate ceramics <i>in vitro</i>.
basic_science · Level V
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- Record sourced from PubMed, PMID 32258831.
- Also identified by DOI 10.1016/j.bioactmat.2020.03.007 and PMC identifier 7118277.
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Abstract
The biocompatibility of biphasic α,β-tricalcium phosphate ceramics, obtained by annealing a compact preform based on β-tricalcium phosphate powder, was studied <i>in vitro</i>. It was found that within 10-30 days the adhesion of primary dental pulp stem cells located on the surface of biphasic α,β-tricalcium phosphate ceramics is suppressed. Decrease of the cell number on the surface of biphasic α,β-tricalcium phosphate ceramics, most likely, can be associated with both the pH level (acidic) as a result of hydrolysis of the more soluble phase of α-tricalcium phosphate and with the nature of surface that changes as a result of the formation and growth of hydroxyapatite crystals.