A Subgroup of Patients With Hospital-acquired Pneumonia Do Not Require Broad-spectrum Gram-negative Antimicrobial Coverage.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 32266388.
- Also identified by DOI 10.1093/cid/ciaa391 and PMC identifier 7744989.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Among 200 patients developing hospital-acquired pneumonia (HAP) outside the intensive care unit, 61% were treated empirically without broad-spectrum Gram-negative coverage, with clinical cure in 69.7%. Lower disease severity markers (systemic inflammatory response syndrome, hypoxia, tachypnoea, neutrophilia) and the absence of diabetes mellitus and prior doxycycline treatment (but not the time to HAP onset) identified patients not requiring broad-spectrum Gram-negative coverage.
Medical subject headings
- Anti-Infective Agents
- Cross Infection
- Healthcare-Associated Pneumonia
- Pneumonia