Early Virus Clearance and Delayed Antibody Response in a Case of Coronavirus Disease 2019 (COVID-19) With a History of Coinfection With Human Immunodeficiency Virus Type 1 and Hepatitis C Virus.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 32270178.
- Also identified by DOI 10.1093/cid/ciaa408 and PMC identifier 7184426.
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Abstract
The effect of host immune status on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection remains unknown. Here, we report the first case of coronavirus disease 2019 (COVID-19) with human immunodeficiency virus type 1 (HIV-1)/hepatitis C virus coinfection, who showed a persistently negative SARS-CoV-2 RNA test but delayed antibody response in the plasma. This case highlights the influence of HIV-1-induced immune dysfunction on early SARS-CoV-2 clearance.
Medical subject headings
- Antibodies, Viral
- COVID-19
- Coinfection
- HIV Infections
- Hepatitis C