Coagulation monitoring and transfusion in major non-emergency orthopaedic surgery - An observational study.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 32280164.
- Also identified by DOI 10.1016/j.jor.2020.03.032 and PMC identifier 7136624.
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Abstract
Perioperative coagulation monitoring and transfusions were evaluated. 70 cases were included. Time points: before (PRE), after surgery (POST), day 1, day 3, day 7. Standard and patient near tests were assessed. Groups were: Transfused (TG); Control (CG). 23 patients were transfused (TG), 47 were not (CG). PRE haemoglobin was reduced, coagulation time (CT) was prolonged in TG. FIBTEM decrease was higher in TG. Leukocytes were elevated in TG. ASPI decreased, TRAP and ADP aggregability increased in both groups. CT, haemoglobin and fibrinogen were associated with transfusion. TRAP and ADP aggregability increased and could account for thromboembolism.