Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 32284613.
- Also identified by DOI 10.1038/s41591-020-0817-4 and PMC identifier 7095102.
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Abstract
We report epidemiological and clinical investigations on ten pediatric SARS-CoV-2 infection cases confirmed by real-time reverse transcription PCR assay of SARS-CoV-2 RNA. Symptoms in these cases were nonspecific and no children required respiratory support or intensive care. Chest X-rays lacked definite signs of pneumonia, a defining feature of the infection in adult cases. Notably, eight children persistently tested positive on rectal swabs even after nasopharyngeal testing was negative, raising the possibility of fecal-oral transmission.
Medical subject headings
- Betacoronavirus
- Coronavirus Infections
- Feces
- Pneumonia, Viral
- Virus Shedding