Positron Emission Tomography Imaging of Poly-(Adenosine Diphosphate-Ribose) Polymerase 1 Expression in Breast Cancer: A Nonrandomized Clinical Trial.

McDonald, Elizabeth S; Doot, Robert K; Pantel, Austin R; Farwell, Michael D; Mach, Robert H; Maxwell, Kara N; Mankoff, David A · JAMA Oncol · 2020

Level II

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Abstract

This nonrandomized clinical trial tested [<sup>18</sup>F]FluorThanatrace as a method for measuring regional poly–(adenosine diphosphate–ribose) polymerase 1 expression in breast cancer and as a potential functional biomarker for breast cancer poly–(adenosine diphosphate–ribose) polymerase inhibitor response.

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