SLeuthing Tuberculous Cough.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 32302566.
- Also identified by DOI 10.1016/j.cell.2020.03.057.
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Abstract
Cough, a hallmark of tuberculosis, transmits the disease. Ruhl et al. find that a Mycobacterium tuberculosis (Mtb)-specific lipid, SL-1, stimulates human nociceptive neurons and makes guinea pigs cough. Mtb extract, but not SL-1, also stimulates non-nociceptive neurons that participate in the cough reflex, suggesting additional cough-inducing mechanisms.
Medical subject headings
- Mycobacterium tuberculosis
- Tuberculosis