HotSpot3D web server: an integrated resource for mutation analysis in protein 3D structures.
Where this comes from
- Record sourced from PubMed, PMID 32315389.
- Also identified by DOI 10.1093/bioinformatics/btaa258.
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Abstract
HotSpot3D is a widely used software for identifying mutation hotspots on the 3D structures of proteins. To further assist users, we developed a new HotSpot3D web server to make this software more versatile, convenient and interactive. The HotSpot3D web server performs data pre-processing, clustering, visualization and log-viewing on one stop. Users can interactively explore each cluster and easily re-visualize the mutational clusters within browsers. We also provide a database that allows users to search and visualize proximal mutations from 33 cancers in the Cancer Genome Atlas. http://niulab.scgrid.cn/HotSpot3D/. Supplementary data are available at Bioinformatics online.
Medical subject headings
- Proteins
- Software