Hypoalbuminemia and generalized edema as an atypical presentation of celiac disease.
case_report · Level V
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- Record sourced from PubMed, PMID 32318495.
- Also identified by DOI 10.4103/jfmpc.jfmpc_1116_19 and PMC identifier 7114008.
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Abstract
The clinical presentation of celiac disease has evolved significantly over the last few decades. Previously defined as a malabsorption syndrome in pediatric patients, now it is considered an autoimmune disorder with diverse systemic manifestations among all age groups. We report a case of 56-year-old male presented with pedal edema and gradually progressive abdomen distention for the last 3 months. Serological evaluation and duodenal biopsy reports were suggestive of celiac disease. The patient was advised gluten-free diet, after 12 weeks, the patient became asymptomatic with the resolution of ascites and peripheral edema. According to the literature, there are few reports of protein-losing enteropathy as an initial presentation of celiac disease. The possibility of celiac disease should be considered even in the setting of atypical symptoms.