Diagnostic Accuracy of QuantiFERON-TB Gold Plus Assays in Children and Adolescents with Tuberculosis Disease.
cross_sectional · Level IV
Where this comes from
- Record sourced from PubMed, PMID 32334890.
- Also identified by DOI 10.1016/j.jpeds.2020.02.025.
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Abstract
In 2016, a new interferon-gamma release assay, QuantiFERON-TB Gold Plus, was introduced. We conducted a cross-sectional multicenter study, involving 158 children and adolescents with tuberculosis disease. The overall sensitivity of the assay was 82.9% (IQR 77.0%-88.8%), indicating that in children this test does not have higher sensitivity than previous generation interferon-gamma release assays.
Medical subject headings
- Interferon-gamma Release Tests
- Mycobacterium tuberculosis
- Tuberculosis