Unexpected BP Sensitivity to Angiotensin II in a Patient With Coronavirus Disease 2019, ARDS, and Septic Shock.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 32335068.
- Also identified by DOI 10.1016/j.chest.2020.04.015 and PMC identifier 7194656.
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Abstract
We report the case of an 88-year-old man with coronavirus disease 2019 (COVID-19) who presented with ARDS and septic shock. The patient had exquisite BP sensitivity to low-dose angiotensin II (Ang-2), allowing for rapid liberation from high-dose vasopressors. We hypothesize that sensitivity to Ang-2 might be related to biological effect of severe acute respiratory syndrome coronavirus 2 infection. The case is suggestive of a potential role for synthetic Ang-2 for patients with COVID-19 and septic shock. Further studies are needed to confirm our observed clinical efficacy.
Medical subject headings
- Angiotensin II
- Angiotensin-Converting Enzyme Inhibitors
- Coronavirus Infections
- Pneumonia, Viral
- Respiratory Distress Syndrome
- Shock, Septic