Antibody responses to SARS-CoV-2 in patients with COVID-19.

Long, Quan-Xin; Liu, Bai-Zhong; Deng, Hai-Jun; Wu, Gui-Cheng; Deng, Kun; Chen, Yao-Kai; Liao, Pu; Qiu, Jing-Fu et al. · Nat Med · 2020

prospective_cohort · Level II

Where this comes from

Abstract

We report acute antibody responses to SARS-CoV-2 in 285 patients with COVID-19. Within 19 days after symptom onset, 100% of patients tested positive for antiviral immunoglobulin-G (IgG). Seroconversion for IgG and IgM occurred simultaneously or sequentially. Both IgG and IgM titers plateaued within 6 days after seroconversion. Serological testing may be helpful for the diagnosis of suspected patients with negative RT-PCR results and for the identification of asymptomatic infections.

Medical subject headings