Interleukin-17: A Social Cytokine.

Hoogenraad, Casper C; Riol-Blanco, Lorena · Cell · 2020

basic_science · Level V

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Abstract

Some children with autism spectrum disorder (ASD) show behavioral improvements when experiencing inflammation accompanied by fever; however, little is known about the mechanisms that underlie these beneficial effects. In a recent issue of Nature, Reed and colleagues demonstrate that the production of interleukin-17 (IL-17) during inflammation promotes social behavior in mouse models of neurodevelopmental disorders.

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