Unusual Manifestation of Chronic Lymphocytic Leukemia in the Hand.

Cruz, Diogo; Wild, Thomas; Glavynskyi, Ievgen; Weissenberg, Kristian; Frenzel, Steffen; Florschütz, Axel; Winter, Jochen · J Hand Surg Am · 2021

case_report · Level V

Where this comes from

Abstract

Chronic lymphocytic leukemia (CLL) involving the hand, especially with bone involvement, is extremely rare. We report a case of a 62-year-old man, with a 4-year history of a subclinical CLL, presenting with chronic swelling and pain over the dorsal surface of the right hand, mimicking an infectious process. There was no clinical response to broad-spectrum antibiotics and topical corticosteroid therapy. Imaging was inconclusive. A tissue biopsy revealed a manifestation of the underlying leukemia. This case highlights the need to consider uncommon etiologies for atypical clinical presentations.

Medical subject headings

Anatomy