Individualized Treatment of Multidrug-resistant Tuberculosis Using Whole-Genome Sequencing and Expanded Drug-Susceptibility Testing.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 32384148.
- Also identified by DOI 10.1093/cid/ciaa526 and PMC identifier 7778351.
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Abstract
A case of multidrug-resistant tuberculosis is presented. It highlights the role of whole-genome sequencing, expanded phenotypic drug susceptibility testing, and enhanced case management, offering a more complete understanding of drug susceptibility to Mycobacterium tuberculosis. This approach guides an effective individualized treatment strategy that results in rapid sustained culture conversion.
Medical subject headings
- Mycobacterium tuberculosis
- Pharmaceutical Preparations
- Tuberculosis, Multidrug-Resistant