Inflammation's Epigenetic Footprint in Hematopoietic Stem Cells.

Geiger, Sarah S; Essers, Marieke A G · Cell Stem Cell · 2020

editorial · Level V

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Abstract

Immune memory was thought to be unique to cells of the adaptive immune system. In this issue of Cell Stem Cell, de Laval et al. (2020) describe persistent epigenetic modifications in hematopoietic stem cells following an inflammatory insult with LPS as a mechanism by which immune memory may be established.

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