Gold-Induced Cytokine (GOLDIC<sup>®</sup>) Injection Therapy in Patient with Plantar Fasciosis: A Case Report.

Melo, Sergio Nicolas Sardon; Ezekwesili, Agnes; Yurdi, Nagib A; Murrell, William D; Maffulli, Nicola · Indian J Orthop · 2020

case_report · Level V

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Abstract

A novel technique of cultivating autologous blood with gold particles; then separating the gold particles and cells from the serum and injecting the conditioned serum into affected plantar fascia. A first-time report of the safety and efficacy in treatment of recalcitrant plantar fasciosis in an Olympic equestrian. A single patient with clinical signs, symptoms and ultrasound evidence of plantar fasciosis was treated with four intra-ligamentous GOLDIC<sup>®</sup> injection therapy. The Olympic jumper was evaluated by Visual Analog Scale (VAS), Foot and Ankle Disability Index (FADI), and Global Rating of Change (GRoC) score(s) before injection and at 6-month follow-up. VAS, FADI, and GRoC scores showed substantial and marked improvement clinically. The subject was able to return to sport without limitations after 8 weeks. The initial result demonstrates that the treatment regimen is safe, and efficacious. The subject demonstrated reduction of pain, and improved function that allowed return to high level competition.