A Global Effort to Define the Human Genetics of Protective Immunity to SARS-CoV-2 Infection.
Where this comes from
- Record sourced from PubMed, PMID 32405102.
- Also identified by DOI 10.1016/j.cell.2020.05.016 and PMC identifier 7218368.
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Abstract
SARS-CoV-2 infection displays immense inter-individual clinical variability, ranging from silent infection to lethal disease. The role of human genetics in determining clinical response to the virus remains unclear. Studies of outliers-individuals remaining uninfected despite viral exposure and healthy young patients with life-threatening disease-present a unique opportunity to reveal human genetic determinants of infection and disease.
Medical subject headings
- Coronavirus Infections
- Genetic Predisposition to Disease
- Pneumonia, Viral