Integrated redox-active reagents for photoinduced regio- and stereoselective fluorocarboborylation.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 32444596.
- Also identified by DOI 10.1038/s41467-020-16477-1 and PMC identifier 7244735.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Vinylboronates and alkylboronates are key components in variegated transformations in all facets of chemical science. The synthesis of vinylboronates and alkylboronates suffers from step-tedious and poor stereoselective procedures. We have developed a regulated radical difunctionalization strategy for the construction of fluorine-containing vinylboronates and alkylboronates with an integrated redox-active reagent IMDN-SO<sub>2</sub>R<sub>F</sub>. This bench-stable imidazolium sulfonate cationic salt offers a scalable and operational protocol for the fluoroalkylation-borylation of unsaturated hydrocarbons in a high regio- and stereoselective manner. The products can be further transformed into valuable fluorinated building blocks.