The UK Biobank imaging enhancement of 100,000 participants: rationale, data collection, management and future directions.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 32457287.
- Also identified by DOI 10.1038/s41467-020-15948-9 and PMC identifier 7250878.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
UK Biobank is a population-based cohort of half a million participants aged 40-69 years recruited between 2006 and 2010. In 2014, UK Biobank started the world's largest multi-modal imaging study, with the aim of re-inviting 100,000 participants to undergo brain, cardiac and abdominal magnetic resonance imaging, dual-energy X-ray absorptiometry and carotid ultrasound. The combination of large-scale multi-modal imaging with extensive phenotypic and genetic data offers an unprecedented resource for scientists to conduct health-related research. This article provides an in-depth overview of the imaging enhancement, including the data collected, how it is managed and processed, and future directions.
Medical subject headings
- Biological Specimen Banks
- Image Enhancement
- Information Management