SnapShot: Ferroptosis.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 32470402.
- Also identified by DOI 10.1016/j.cell.2020.04.039 and PMC identifier 8157339.
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Abstract
Ferroptosis is a regulated form of cell death that occurs when phospholipids with polyunsaturated fatty acyl tails are oxidized in an iron-dependent manner. Research in recent years has uncovered complex cellular networks that induce and suppress lethal lipid peroxidation. This SnapShot provides an overview of ferroptosis-related pathways, including relevant biomolecules and small-molecule modulators regulating them.
Medical subject headings
- Ferroptosis
- Iron