Introductions and early spread of SARS-CoV-2 in the New York City area.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 32471856.
- Also identified by DOI 10.1126/science.abc1917 and PMC identifier 7259823.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
New York City (NYC) has emerged as one of the epicenters of the current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. To identify the early transmission events underlying the rapid spread of the virus in the NYC metropolitan area, we sequenced the virus that causes coronavirus disease 2019 (COVID-19) in patients seeking care at the Mount Sinai Health System. Phylogenetic analysis of 84 distinct SARS-CoV-2 genomes indicates multiple, independent, but isolated introductions mainly from Europe and other parts of the United States. Moreover, we found evidence for community transmission of SARS-CoV-2 as suggested by clusters of related viruses found in patients living in different neighborhoods of the city.
Medical subject headings
- Betacoronavirus
- Coronavirus Infections
- Genome, Viral
- Pneumonia, Viral