Molecular Imaging of Cardiac Amyloidosis.
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- Record sourced from PubMed, PMID 32482792.
- Also identified by DOI 10.2967/jnumed.120.245381 and PMC identifier 9374028.
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Abstract
Transthyretin and light-chain amyloidosis are the 2 main causes of cardiac amyloidosis. Recent developments in molecular imaging have transformed our ability to diagnose transthyretin cardiac amyloidosis noninvasively and unmasked a hitherto unrecognized prevalence of the disease. This review summarizes the current and evolving imaging approaches, their molecular structural basis, and the gaps in imaging capabilities that have arisen as a result of parallel developments in pharmacotherapy delivering the first effective treatment options for this condition.
Medical subject headings
- Amyloidosis
- Cardiomyopathies
- Molecular Imaging