Break on Through: Golgi-Derived Vesicles Aid in Mitochondrial Fission.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 32492390.
- Also identified by DOI 10.1016/j.cmet.2020.05.010 and PMC identifier 8212386.
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Abstract
Mitochondrial fission is sustained through contact with several organelles, including the endoplasmic reticulum, lysosomes, and the actin cytoskeleton. Nagashima et al. (2020) now demonstrate that PI(4)P-containing Golgi-derived vesicles also modulate mitochondrial fission, driven by Arf1 and PI(4)KIIIβ activity, identifying a new organelle contact involved in maintaining mitochondrial homeostasis.
Medical subject headings
- Golgi Apparatus
- Mitochondrial Dynamics