Lipase Elevation in Patients With COVID-19.

McNabb-Baltar, Julia; Jin, David X; Grover, Amit S; Redd, Walker D; Zhou, Joyce C; Hathorn, Kelly E; McCarty, Thomas R; Bazarbashi, Ahmad N et al. · Am J Gastroenterol · 2020

retrospective_cohort · Level III

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Abstract

Although coronavirus disease (COVID-19) has been associated with gastrointestinal manifestations, its effect on the pancreas remains unclear. We aimed to assess the frequency and characteristics of hyperlipasemia in patients with COVID-19. A retrospective cohort study of hospitalized patients across 6 US centers with COVID-19. Of 71 patients, 9 (12.1%) developed hyperlipasemia, with 2 (2.8%) greater than 3 times upper limit of normal. No patient developed acute pancreatitis. Hyperlipasemia was not associated with poor outcomes or symptoms. Although a mild elevation in serum lipase was observed in some patients with COVID-19, clinical acute pancreatitis was not seen.

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