Colon Cancer Heterogeneity: Welcome to the RiboZone.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 32502398.
- Also identified by DOI 10.1016/j.stem.2020.05.005.
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Abstract
In this issue of Cell Stem Cell, Morral et al. (2020) shed new light on the hierarchical organization of cells within colorectal cancer. They show that tumor cells at the apex of this hierarchy reside in particular tumor zones and possess high protein synthesis activity. Interference with their biosynthetic activity results in an irreversible growth arrest of CRC.
Medical subject headings
- Colonic Neoplasms
- Colorectal Neoplasms