There's No I in Team: Cellular Crosstalk Enhances In Vitro Cardiac Maturation.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 32502399.
- Also identified by DOI 10.1016/j.stem.2020.05.009.
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Abstract
Organoids and microtissues offer the unique opportunity to dissect cell-cell interactions in an organ-specific context without confounding effects of organ failure or organism viability. In a study in this issue of Cell Stem Cell, Giacomelli et al. (2020) add human cardiac fibroblasts into cardiac microtissues and reveal striking fibroblast-endothelial-cardiomyocyte crosstalk that promotes advanced cardiomyocyte maturation.
Medical subject headings
- Heart Diseases
- Induced Pluripotent Stem Cells