New (re)purpose for an old drug: purinergic modulation may extinguish the COVID-19 thromboinflammatory firestorm.
Level V
Where this comes from
- Record sourced from PubMed, PMID 32530438.
- Also identified by DOI 10.1172/jci.insight.140971 and PMC identifier 7453890.
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Abstract
Purinergic signaling is discussed as a potential therapeutic target to reduced COVID-19 severity.
Medical subject headings
- Coronavirus Infections
- Cytokine Release Syndrome
- Dipyridamole
- Pneumonia, Viral
- Purinergic Agents
- Thrombosis