Psoriasis-associated impairment of CCL27/CCR10-derived regulation leads to IL-17A/IL-22-producing skin T-cell overactivation.
Where this comes from
- Record sourced from PubMed, PMID 32533971.
- Also identified by DOI 10.1016/j.jaci.2020.05.044 and PMC identifier 7726097.
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Abstract
Psoriasis-associated suppression of the skin-specific chemokine/receptor CCL27/CCR10 axis leads to enhanced pathogenic IL-17A/IL-22-producing skin T cell activation and inflammation.
Medical subject headings
- Chemokine CCL27
- Lymphocyte Activation
- Psoriasis
- Receptors, CCR10
- T-Lymphocytes