Targeted protection of proximal tubular cells by nanoparticle-enhanced delivery of a TLR9-antagonist.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 32571488.
- Also identified by DOI 10.1016/j.kint.2020.04.024.
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Abstract
The kidney target site for injury that leads to acute kidney injury (AKI) is the proximal tubule. Nanoparticle-encapsulation enhanced delivery of a selective Toll-like receptor 9 antagonist to mouse proximal tubules and attenuated experimental ischemia-reperfusion injury in a mouse model of AKI.
Medical subject headings
- Acute Kidney Injury
- Nanoparticles
- Reperfusion Injury