Age-Induced Reduction in Human Lipolysis: A Potential Role for Adipocyte Noradrenaline Degradation.
Level V
Where this comes from
- Record sourced from PubMed, PMID 32589948.
- Also identified by DOI 10.1016/j.cmet.2020.06.007.
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Abstract
Gao et al. report that the observed reduction in adipose lipolysis with age in women could be explained by an upregulation of the catecholamine-degradation pathway in subcutaneous adipocytes. However, in contrast to findings in mice, these pathways are enriched in adipocytes and not in immune cells, suggesting species-specific differences in aging mechanisms.
Medical subject headings
- Inflammasomes
- Lipolysis