Role of Microbiota-Derived Bile Acids in Enteric Infections.

Theriot, Casey M; Petri, William A · Cell · 2020

editorial · Level V

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Abstract

In this issue of Cell, Alavi et al. report that infection by Vibrio cholerae is blocked by gut microbiome-mediated hydrolysis of bile acids. Cholera therefore joins amebic dysentery and Clostridioides difficile colitis as enteric infections profoundly influenced by the microbiome's impact on bile acid metabolism.

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