The Utility of IgA-Based Serologic Markers in Diagnosing Celiac Disease in Children 24 Months of Age or Younger.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 32593411.
- Also identified by DOI 10.1016/j.jpeds.2020.04.009 and PMC identifier 7819766.
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Abstract
Current screening guidelines in North America for celiac disease recommend additional IgG based testing for younger children. Our multicenter retrospective study showed that the anti-tissue transglutaminase IgA antibody test should be the recommended initial test in all children, including those ≤24 months of age.
Medical subject headings
- Celiac Disease
- GTP-Binding Proteins
- Transglutaminases