Steep Rebound of Chloroquine-Sensitive Plasmodium falciparum in Zimbabwe.
Where this comes from
- Record sourced from PubMed, PMID 32594154.
- Also identified by DOI 10.1093/infdis/jiaa368 and PMC identifier 7857352.
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Abstract
Removal of chloroquine from national malaria formularies can lead to the reversion of resistant Plasmodium falciparum to wild-type. We report a steep decline in chloroquine-resistant P falciparum within 10 years of national discontinuation of chloroquine monotherapy in Zimbabwe. Drug resistance surveillance is a vital component of malaria control programs, and the experience with chloroquine in Zimbabwe and elsewhere in sub-Saharan Africa is illustrative of the potentially rapid and dramatic impact of drug policy on antimalarial resistance.
Medical subject headings
- Chloroquine
- Drug Resistance
- Malaria, Falciparum
- Parasite Load
- Plasmodium falciparum