Bronchoscopic Treatment of Tracheobronchial Fistula With Autologous Platelet-Rich Plasma.

Wu, Meirong; Lin, Huihuang; Shi, Liyong; Huang, Linlin; Zhuang, Yawen; Zeng, Yiming · Ann Thorac Surg · 2021

case_report · Level V

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Abstract

Tracheobronchial fistula (TBF) is a challenging management condition. Several bronchoscopic procedures have been tried for fistula closure. However, none has been found to be superior to the others. We herein describe a novel technique involving the submucosal injection of autologous platelet-rich plasma (auto-PRP) around the fistula to close the TBF. After auto-PRP treatment, all 3 TBF patients have successfully healed. No treatment-related complications and fistula-related symptoms were detected. Thus, this application of auto-PRP for fistula closure is a feasible and cost-effective strategy and could be recommended as a valuable therapeutic alternative for repairing postoperative TBF.

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