Infections in Patients Colonized With Extended-spectrum Beta-Lactamase-Producing Enterobacterales: A Retrospective Cohort Study.

Vock, Isabelle; Aguilar-Bultet, Lisandra; Egli, Adrian; Tamma, Pranita D; Tschudin-Sutter, Sarah · Clin Infect Dis · 2021

retrospective_cohort · Level III

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Abstract

We investigated relative proportions of extended-spectrum beta-lactamase-producing Enterobacterales (ESBL-PE) versus non-ESBL-PE (nESBL-PE) infections in ESBL-PE colonized patients. ESBL-PE are not causative for the majority of infections in hospitalized patients colonized with ESBL-PE. Site of infection and patient-level exposures may be useful predictors of nESBL-PE infections, potentially guiding empiric treatment recommendations.

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