Outcomes of Reflex Cryptococcal Antigen (CrAg) Screening in Human Immunodeficiency Virus (HIV)-Positive Patients With CD4 Counts of 100-200 Cells/µL in Botswana.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 32604411.
- Also identified by DOI 10.1093/cid/ciaa899 and PMC identifier 8096249.
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Abstract
Increasing the CD4-count threshold for cryptococcal antigen (CrAg) screening from ≤100 to ≤200 cells/µL resulted in a 3-fold increase in numbers screened. CrAg-prevalence was 3.5% at CD4 101-200 and 6.2% ≤100 cells/µL. Six-month mortality was 21.4% (9/42) in CrAg-positive CD4 ≤100 cells/µL and 3.2% (1/31) in CrAg-positive CD4 101-200 cells/µL.
Medical subject headings
- AIDS-Related Opportunistic Infections
- Cryptococcus
- HIV Infections
- Meningitis, Cryptococcal