SARS-CoV-2 Infection in Patients with Down Syndrome, Congenital Heart Disease, and Pulmonary Hypertension: Is Down Syndrome a Risk Factor?

Krishnan, Usha S; Krishnan, Sankaran S; Jain, Shipra; Chavolla-Calderon, Mara B; Lewis, Matthew; Chung, Wendy K; Rosenzweig, Erika B · J Pediatr · 2020

case_series · Level IV

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Abstract

With increasing information available about the epidemiology, pathophysiology, and management of patients affected with severe acute respiratory syndrome corona virus-2 infection, patients with Down syndrome, congenital heart disease, airway obstruction, and pulmonary hypertension present a unique challenge. This case series describes 3 patients with Down syndrome and respiratory failure secondary to coronavirus infection.

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